![]() ![]() Kuhlmann and colleagues obtained data and blood samples from 106 people, each of whom participated in one of four such studies. Nonetheless, any remaining healthy participants also were given antibiotics to clear the bacteria before going home. The disease comes on quickly, so anyone who was still healthy at the end of five days was unlikely to get sick later. Those who developed moderate to severe diarrhea were treated with antibiotics. Then, they observed the volunteers for five days. coli strain originally isolated from a person in Bangladesh with severe, cholera-like diarrhea. In controlled human infection clinical trials, researchers at Johns Hopkins University gave healthy volunteers a dose of an E. Fleckenstein, instructor in medicine Matthew Kuhlmann, MD, postdoctoral researcher Pardeep Kumar, PhD, and colleagues investigated whether blood type influences disease severity by looking at what happened to people of different blood types who drank a cup of water laced with E. coli in Bangladesh seemed to get sicker if they had blood type A, but the reason for this was never tested. Years ago, doctors noted that children naturally infected with enterotoxigenic E. That outbreak involves a different kind of E. coli are not the cause of the current romaine lettuce-related outbreak. Others experience unpleasant symptoms but recover easily, while some don’t get sick at all.Įnterotoxigenic E. Some people infected with the bacterium develop severe, cholera-like, watery diarrhea that can be lethal. It primarily infects people living in or visiting developing countries. coli are responsible for millions of cases of diarrhea and hundreds of thousands of deaths every year, mainly of young children. The work was conducted in collaboration with investigators at Johns Hopkins University, the National Institutes of Health (NIH), and the Naval Medical Research Center.Įnterotoxigenic E. The study is published May 17 in The Journal of Clinical Investigation. “A vaccine targeting this protein would potentially protect the individuals at highest risk for severe disease.” “We think this protein is responsible for this blood-group difference in disease severity,” said senior author James Fleckenstein, MD, an associate professor of medicine at Washington University. A vaccine targeting that protein could potentially protect people with type A blood against the deadliest effects of enterotoxigenic E. The bacteria release a protein that latches onto intestinal cells in people with blood type A, but not blood type O or B, according to a study led by researchers at Washington University School of Medicine in St. coli most associated with “travelers’ diarrhea” and children in underdeveloped areas of the world causes more severe disease in people with blood type A. ![]() The findings could potentially lead to a vaccine to help protect people living in or visiting developing countries.Ī new study shows that a kind of E. coli (shown in a computer-generated image above) than people with blood group O or B. People with blood group A are more likely to develop severe diarrhea when infected with a kind of E. Alissa Eckert and Jennifer Oosthuizen/CDC.Researchers ID protein responsible for blood-group differenceīy Tamara Bhandari News Release Blood type affects severity of diarrhea caused by E. ![]()
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![]() Here, he attempts to marry classical Baroque forms (prelude, fugue) with jazz, though the latter style very much dominates proceedings. This is one of Leonard Bernstein’s most frequently performed shorter concert works, a great favourite with wind ensembles. ‘Lamentation’.Ĭlick to load video 9: Prelude, Fugue and Riffs (1949) Jeremiah’s Lamentations express his deep sorrow over the resulting desolation, as well as hope for the people of God. His prophecy was fulfilled when Solomon’s Temple was destroyed and Jerusalem fell to the Babylonians in 587 BC. In this, the prophet Jeremiah warned the Israelites that their sinfulness would lead to disaster. The soprano was supplanted by a mezzo-soprano whose sung text comes from the Book of Lamentations. I then realized that this movement, and the Scherzo that I planned to follow it, made logical concomitants with the Lamentation.” This sketch lay forgotten for two years until, in the spring of 1942, I began a first movement of a symphony. Leonard Bernstein himself explained how the Symphony came into being: “In the summer of 1939, I made a sketch for a Lamentation for soprano and orchestra. It led to a rapprochement between father and son, leading the young composer to dedicate ‘Jeremiah’ to his father. When he saw the overwhelming response of the audience that afternoon at Carnegie Hall, he came backstage, overcome with emotion. It was this work that established Leonard Bernstein as an important American symphonist – and indeed sealed his position as a leading American musician – for the premiere of the ‘Jeremiah’ Symphony in January 1944 came just a few months after Bernstein’s legendary conducting debut with the New York Philharmonic when he became the last-minute stand-in for Bruno Walter.īernstein’s father Sam had not been supportive of his son’s musical ambitions. ![]() Listen to Leonard Bernstein Conducts West Side Story on Apple Music and Spotify. Scroll down to discover our selection of the best Bernstein works featuring ten masterpieces by the great composer. There is also no doubt about his status as one of the great maestros of the twentieth century, and classical music’s most accomplished communicators, able to explore and explain the most complex ideas to young audiences. ![]() How enduring his works will be, only history will tell, but at least one composition, West Side Story, is an unquestionable masterpiece. Leonard Bernstein (25 August 1918 – 14 October 1990) was an American conductor, composer, pianist, writer, teacher, educationalist, activist and one of the most important figures of his generation in the musical life of his country. ![]() ![]() ![]() Prizmo exports to text, RTF, searchable PDF, and image files, but not to spreadsheet or HTML format as FineReader Express does. Finally, at the far right end of the toolbar-and what felt a bit like the end of a quest-I could click an Export button and save the recognized text to Evernote, Box.com, Dropbox, Google Drive, any other WebDAV drive, an e-mail recipient, or-as in traditional OCR-a file. There's also a button for reading the extracted text aloud, using OS X's built-in speech feature, and for translating the extracted text into any of dozens of languages, though a built-in connection with Microsoft's translation service. I could use this pane to make manual corrections to the recognized text before exporting it-a feature not available in ABBYY FineReader Express.Īlso, in this Recognition window, a new toolbar replaced the original one, with icons for adding, removing, and reordering the regions identified by the app. After I clicked the Recognize button, the app overlaid the image with rectangles showing where it detected text, and opened a pane next to the image with the text that the app had extracted. When I clicked that button, the color image changed from color to black and white, showing the black text that the program would now recognize when I clicked yet another button, this one marked Recognize.Īs you can guess from this report, there are plenty of underdocumented steps that you need to perform to get the best possible results, and we're not through yet. Toolbar icons let me rotate, crop, or make brightness and other adjustments to the image before clicking the OCR button. An optional preference automatically applied distortion correction to the image based on the geometry of the iPhone's camera lens. ![]() In ActionWhen I snapped a picture with an iPhone plugged into my Mac, the picture instantly appeared in Prizmo's window. The third takes you to your iPhoto library and the Pictures folder in your user folder. The second opens OS X's scanner dialog and lets you work from a scanner. But after I clicked that button, Prizmo showed me a spacious window with the message "Drop a Picture of Text Here" and three further options: "Open Image File.", "Import from Scanner or Camera." and "Browse Image Library." The first option works as you expect: select a PDF, PNG, JPG, or any other standard image format and open it in Prizmo's window. I finally figured out that I needed to click the "New Document" button at the foot of the window, which was also slightly puzzling since I didn't realize I was creating a document-I thought I was perform OCR on an image. Puzzling PrizmoI was slightly puzzled when I launched Prizmo because it required me either to open an existing Prizmo document from iCloud or my Mac, but of course I didn't have any Prizmo documents since I had never run it before. ![]() ![]() ![]() Z2 = D - w2 * wOctet - x2 * xOctet - y2 * yOctet Y2 = math.floor((D - w2 * wOctet - x2 * xOctet) / yOctet) ![]() X2 = math.floor((D - w2 * wOctet) / xOctet) G=int(input("Now supply the prefix length of your gateway subnet: "))ĭ = w * wOctet x * xOctet y * yOctet z Print("Please supply your virtual network address space in the form of w.x.y.z/n.") Print("*** Gateway subnet address space calculator for Azure virtual networks ***") # Collect the values of w.x.y.z/n for your VNet address space and g, the prefix length of your gateway subnet Use this code block to create a console app in Python. Z2 = d - w2 * wOctet - x2 * xOctet - y2 * yOctet Ĭonsole.WriteLine("For the Azure virtual address space ", w2, x2, y2, z2, gwPrefLen) Ĭonsole.WriteLine("Press ENTER to quit.") Y2 = (d - w2 * wOctet - x2 * xOctet) / yOctet GwPrefLen = Convert.ToInt32(Console.ReadLine()) ĭ = w * wOctet x * xOctet y * yOctet z įor (int i = vnetPrefLen 1 i < gwPrefLen 1 i ) VnetPrefLen = Convert.ToInt32(Console.ReadLine()) Ĭonsole.WriteLine("Now supply the prefix length of your gateway subnet:") ![]() ![]() Super Meat Boy Forever is an amazing, Adventure, Platform, Side-scroll and Single-player video game developed and published by Team Meat for Nintendo Switch. ![]() Try it out and see if you can survive in harsh physical environments and can solve the twisted puzzles. ![]() Never Alone offers a story deeply inspired by Alaskan Folklore, that includes sub stories such as Blizzard man, The Little People, Manslayer, The Rolling Heads, The Sky People etc. Never Alone lets you use Bola, a special weapon made with weights and interconnected cords to smash into closed areas and open them up, get into new environments and enjoy immersing yourself into an amazingly addictive and quite engaging gameplay. Exploration element of the game lets you explore the game world, interact with objects and solve various puzzles based on physics and environmental wonders. Never Alone lets you swap between the two characters (Nuna and Fox) according to the puzzles in front of you and lets you pick different objects, solve puzzles and restore the balance in the core of Eternal Blizzard. The game offers a game-play divided into 8 chapters and allows you to be an Alaskan Eskimo girl named as Nuna who along with her Companion, an Arctic Fox follows the stories in every chapter and completes various and challenging puzzles. Never Alone is a Single Player, Local Co-operative, Atmospheric Puzzle-Platform video game by Upper One Games. It offers a brilliantly immersive gameplay, a well-written story and a lot of other great things to enjoy. If you really want to play a really good game of Action-Adventure and Puzzle-Platform genres, Child of Light is best for you. Child of Light offers a great story filled with wonders, surreal visuals and sounds and an immersive game-play for you to play and enjoy. You are required to get into the role of Aurora, fight off all the Dark Creatures, Defeat the Queen of Night and free the Sun in order to bring light to the realm and finally reach home. After waking up she finds out that she is a long way from home, starts off her journey to her home but soon realizes that in order to reach home she’ll have to go through a Dark world filled with Dark Creatures of the evil queen of the Night. World of Goo Corporation is contractually obligated to state that everyone is a winner and is enthusiastic to celebrate everyone's tower building opportunities equally.Child of Light by Ubisoft Montreal is a marvelous Action-Adventure, Indie and Puzzle-Platform video game that tells the story of a young girl named Aurora who in the year 1895 awakens on the lands of Lemuria.
![]() If your workplace has an accident, OSHA audits and investigations are likely. Our system helps reduce your forklift certification cost. With our Internet-based training platform, there are no books, no costly offsite training centers to rent, no expensive 3rd party instructors. training works with your schedule – not the other way around! Our forklift license programs offer ultimate flexibility. Here are a few reasons why is the preferred forklift certification provider for companies all across the United States: Aside from our safety compliance training, affordable prices, and insider OSHA expertise, makes sense in so many ways. We’re the experts in how to get forklift certified. Your employee does not have to go off-site for their online forklift certification, this reduces staff downtime and also minimizes your potential liability for off-site conduct
![]() Media critics, fueled by Trump or otherwise, would like to dislodge societal norms that the traditional news media strives to be fair and objective. A steady barrage of tweets by President Donald Trump about “fake news” and the “fake news media” has put the role and credibility of the media front and center in the public eye. Whether they feel that the closed settings of college campuses require special handling, or whether they believe more broadly that hateful speech has no place in society, remains a question for future consideration.įew controversies are louder or more visible today than attention to the role and credibility of the news media. This segment of the student population does not buy into the open dialogue paradigm for free speech when the speakers are targeting minority groups. Some part of the current generation of students, population size unknown, believes that they should not have to listen to offensive speech that targets oppressed elements of society for scorn and derision. Whether they are a new phenomenon or more numerous than in the past may be beside the point. The campus controversies may be an example of freedom of speech in flux. But those controversies have garnered prominent national attention, and some examples are reflected in this issue of Human Rights. On balance, there is certainly vastly more free exchange of ideas that takes place on campuses today than the relatively small number of controversies or speakers who were banned or shut down by protests. The dichotomy-society generally favoring free speech, but individuals objecting to the protection of particular messages-and the debate over it seem likely to continue unabated.Ī related contemporary free speech issue is raised in debates on college campuses about whether schools should prohibit speeches by speakers whose messages are offensive to student groups on similar grounds of race and gender hostility. Offensive speech that creates a hostile work environment or that disrupts school classrooms may be prohibited.īut apart from those exceptions, the Supreme Court has held strongly to the view that our nation believes in the public exchange of ideas and open debate, that the response to offensive speech is to speak in response. Hateful speech that threatens or incites lawlessness or that contributes to motive for a criminal act may, in some instances, be punished as part of a hate crime, but not simply as offensive speech. With the raised awareness come increased calls for laws punishing speech that is racially harmful or that is offensive based on gender or gender identity.Īt present, contrary to widely held misimpressions, there is not a category of speech known as “hate speech” that may uniformly be prohibited or punished. These movements have raised consciousness and promoted national dialogue about racism, sexual harassment, and more. The controversy over what many call “hate speech” is not new, but it is renewed as our nation experiences the Black Lives Matter movement and the Me Too movement. Surveys traditionally show that the American people have strong support for free speech in general, but that number decreases when the poll focuses on particular forms of controversial speech. As longtime law professor, free speech advocate, author, and former American Civil Liberties Union national president Nadine Strossen notes in her article, there has long been a dichotomy in public opinion about free speech. ![]() ![]() One point of regular debate is whether there is a free speech breaking point, a line at which the hateful or harmful or controversial nature of speech should cause it to lose constitutional protection under the First Amendment. This is not meant to be a comprehensive survey of First Amendment developments, but rather a smorgasbord of interesting issues. This issue of Human Rights explores contemporary issues, controversies, and court rulings about freedom of speech and press. ![]() Constitution were ratified in 1791 as the Bill of Rights, debate continues about the meaning of freedom of speech and its First Amendment companion, freedom of the press. Yet 227 years after the first 10 amendments to the U.S. Freedom of speech, Supreme Court Justice Benjamin Cardozo declared more than 80 years ago, “is the matrix, the indispensable condition of nearly every other form of freedom.” Countless other justices, commentators, philosophers, and more have waxed eloquent for decades over the critically important role that freedom of speech plays in promoting and maintaining democracy. ![]() ![]() In sound, as you know, the waves are air movement in waves and our ears convert these to electrical waves to be interpreted by our brain. As a new wave moves forward from a steady source of disturbance, in the center or the pool, and a reflection wave bouncing back off the wall, or reflected back to the source, meet at some point along the way… these two wave fronts commingle some combine positively (creating peaks higher than either original) or negatively (producing troughs or valleys). You can also think about standing waves in a small pool. The term “beats” is the clue… a beat frequency is one that arises from the addition and subtraction between the two fundamental frequencies being linearly “mixed” or, more accurately, “combined”. Check our second guide on How to lucid dream with binaural beats! For example, if you like using the WILD technique, you can start listening to them after your early alarm wakes you up. Now you’ve set everything up, you can use your desired lucid dreaming technique, such as the WILD or DILD.īinaural beats are very versatile and can be used when you go to bed at night or when you’re waking up early during your REM phase of sleep. Now is the time to employ a visualization technique, or repeat (in your mind) an affirmation over and over again.Īn example of a good affirmation would be “I’m becoming aware of my dreams.” 6) Further lucid dreaming technique What this means is that, while you’re incredibly relaxed, you’ll still have power over your thoughts. ![]() – After a while, you will hopefully find yourself in a very tranquil, yet slightly focused state. 4) Combine with a visualization or affirmation technique Just ensure your stresses are evaporating into thin air as your mind and body relaxes. – It doesn’t matter whether you focus on your breathing, the sounds that you’re listening to, or whatever. Ideally, you want to use delta wave binaural beats (between 4Hz – 8hz). ![]() – Listen to your binaural beats recording with headphones. ![]() A comfy mattress or soft couch will make all the difference. – Lay down and ensure you’re in a comfortable position. ![]() ![]() ![]() Library ( plotly ) #Initialize figures fig1 % layout ( xaxis = list ( title = 'xaxis1 title' ), yaxis = list ( title = 'yaxis1 title' )) fig2 % layout ( xaxis = list ( title = 'xaxis2 title', range = c ( 10, 50 )), yaxis = list ( title = 'yaxis2 title', range = c ( 40, 80 ))) fig3 % layout ( xaxis = list ( title = 'xaxis3 title', showgrid = FALSE ), yaxis = list ( title = 'yaxis3 title', showgrid = FALSE )) fig4 % layout ( xaxis = list ( title = 'xaxis4 title', type = 'log' ), yaxis = list ( title = 'yaxis4 title' )) #creating subplot fig % layout ( title = 'Customizing Subplot Axes', plot_bgcolor = '#e5ecf6', xaxis = list ( zerolinecolor = '#ffff', zerolinewidth = 2, gridcolor = 'ffff' ), yaxis = list ( zerolinecolor = '#ffff', zerolinewidth = 2, gridcolor = 'ffff' )) # Update title annotations = list ( list ( x = 0.2, y = 1.0, text = "Plot 1", xref = "paper", yref = "paper", xanchor = "center", yanchor = "bottom", showarrow = FALSE ), list ( x = 0.8, y = 1, text = "Plot 2", xref = "paper", yref = "paper", xanchor = "center", yanchor = "bottom", showarrow = FALSE ), list ( x = 0.2, y = 0.4, text = "Plot 3", xref = "paper", yref = "paper", xanchor = "center", yanchor = "bottom", showarrow = FALSE ), list ( x = 0.8, y = 0.4, text = "Plot 4", xref = "paper", yref = "paper", xanchor = "center", yanchor = "bottom", showarrow = FALSE )) fig % layout ( annotations = annotations ) fig ![]() Here is an example that creates a figure with a 2 x 2 subplot grid, populates each subplot with a scatter trace, and then updates the x and y axis titles for each subplot individually. The row and col arguments can be used to control which axes are targeted by the update. ![]() By default, these methods apply to all of the x axes or y axes in the figure. ![]() Customizing Subplot AxesĪfter a figure with subplots is created using the subplot function, its axis properties (title, font, range, grid style, etc.) can be customized using the xaxis and yaxis graph object figure methods. Library ( dash ) library ( dashCoreComponents ) library ( dashHtmlComponents ) library ( plotly ) app <- Dash $ new () app $ layout ( htmlDiv ( list ( dccGraph ( id = 'graph-with-slider' ), htmlLabel ( 'Subplots Width:' ), dccSlider ( id = 'slider', min = 0, max = 1, value = 0.5, step = 0.01 ) ) ) ) app $ callback ( output ( id = 'graph-with-slider', property = 'figure' ), params = list ( input ( id = 'slider', property = 'value' )), function ( value ) )Īfter executing this code, give app$run_server() in the console to start the dash. Library ( plotly ) fig1 % layout ( title = 'Multiple Subplots with Titles', plot_bgcolor = '#e5ecf6', xaxis = list ( zerolinecolor = '#ffff', zerolinewidth = 2, gridcolor = 'ffff' ), yaxis = list ( zerolinecolor = '#ffff', zerolinewidth = 2, gridcolor = 'ffff' )) annotations = list ( list ( x = 0.2, y = 1.0, text = "Plot 1", xref = "paper", yref = "paper", xanchor = "center", yanchor = "bottom", showarrow = FALSE ), list ( x = 0.8, y = 1, text = "Plot 2", xref = "paper", yref = "paper", xanchor = "center", yanchor = "bottom", showarrow = FALSE ), list ( x = 0.2, y = 0.45, text = "Plot 3", xref = "paper", yref = "paper", xanchor = "center", yanchor = "bottom", showarrow = FALSE ), list ( x = 0.8, y = 0.45, text = "Plot 4", xref = "paper", yref = "paper", xanchor = "center", yanchor = "bottom", showarrow = FALSE )) fig % layout ( annotations = annotations ) #options(warn = -1) fig ![]() ![]() ![]() Above Right: Egg yolk wash and granulated sugar.Results: Another nice shiny brown surface, and again, it seems to seal the crust. ![]() Results: The sugar melts and creates a crunchy surface that cracks when you bite it.
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